Stem cells are the basic building blocks of the body that can become any other type of cell.

They are also responsible for the renewal and repair work in all parts of your body, including your skin. Stem cells are thus essential in keeping your body and skin youthful and healthy.

Aging takes place when the quantity and quality of stem cells diminish as we get older. This leads to your body’s weakened ability to combat the daily ravages of the environment and resist the effects of gravity on your skin. Skin that is not able to produce enough glycoproteins, such as hyaluronic acid and elastin at the dermal layer starts to sag. Skin function suffers when stem cells are no longer sending messages to the epidermal layer to renew itself; this leads to a dry, crepey surface that accumulates pigmentation.

CALECIM® Professional is the world’s only skincare that is powered by stem cells from the umbilical cord lining. Proteins, comprised of powerful growth factors and cytokines, are secreted from this patented source of stem cells, and make up the active ingredient in the range of CALECIM® Professional cosmeceuticals.

Let’s take a look at why CALECIM® Professional’s source of stem cells is so unique and relevant to skin revitalization, and how its active ingredients can help maintain your skin’s tightness, elasticity, radiance, and overall health.

Umbilical Cord Lining Produces Two Types of Stem Cells

There are two types of stem cells in the lining membrane of the umbilical cord, which can potentially differentiate into many different cells:
Epithelial stem cells — are able to morph into surface lining cells, such as the epidermal layer of the skin.
Mesenchymal stem cells — can differentiate into structural cells such as your inner organs, nerve, fat, or cartilage, as well as the dermal layer of skin.

Because of their ability to constitute the entire structure of the skin, from the dermis to epidermis, mesenchymal and epithelial stem cells are your essential tools in renewing and repairing your skin, helping keep aging at bay. Stem cells do their work by sending out proteins that communicate with skin cells. These proteins act as messages that regulate skin function, signalling old skin cells to shed, and new cells to proliferate. Stem cells are also the command centre for action when a wound or traumatic injury is sustained; sending out messages for surrounding skin cells to move towards one another to close the wound, and encouraging the production of new skin cells.

Skin and Aging

When you are young, the young stem cells within you are extremely efficient and vigorous in producing and sending messages to your skin, encouraging it to renew itself regularly. In young and healthy skin, complete epidermal cell turnover takes place every 28 days. With aging, stem cell signals drop, which leads to a sluggish skin cell turnover. It is not uncommon for aged skin epidermal cell turnover to slow to 40 days or more. Old skin cells that remain on the surface of your skin lose their water retention ability and start to accumulate pigment. The result is a crepey, dry and rough surface with discoloration.

Reduced stem cell signalling also means that the dermal layers are affected with reduced production of all the glycoproteins that are needed for your skin to retain moisture, and elastin to defy gravity.

What is lost from your dermal layers are:

Skin-strengthening collagen that provides skin with shape and volume

Elastin that provides skin with pliability and resilience

Skin-hydrating hyaluronic acid that allows skin to hold on to moisture so that it is plump and radiant

CALECIM® Professional Skin Rejuvenating Creams 

For the consistent and healthy renewal of cells that are crucial to maintaining your skin’s radiance, smoothness, and firmness, CALECIM® Professional delivers the active ingredient that can accelerate the skin’s cellular revitalization. The proprietary formula in each of CALECIM® Professional’s rejuvenative creams is derived from stem cell proteins extracted from umbilical cord lining stem cells. These proteins help:
Enhance skin shape
Restore skin volume
Improve skin resiliency
Increase skin moisture
Minimize facial lines and wrinkles

CALECIM® Professional treatment creams are rich in stem cell proteins that promote regular cycles of cell production and cell shedding, as well as to encourage glycoprotein production, to notably renew, revive and restore skin in as little as two weeks.

Daily Application of CALECIM® Professional Multi-Action Cream Targets Signs of Aging

The unique blend of proteins produced by the stem cells from umbilical cord lining is rich in the following ingredients: 

Essential Proteins which are responsible for sending out the signals that regulate skin function Collagen to strengthen and contour the skin 

Collagen-supporting fibronectin 

Hyaluronic acid to hydrate and volumize the skin 

CALECIM® Professional Restorative Hydration Cream Provides Optimal Hydration

Restorative Hydration Cream, which is enriched with water based aloe vera in addition to stem cell-derived hyaluronic acid, allows skin to restore optimal levels of hydration necessary for skin renewal and youthful radiance.

When used together, Multi-Action Cream and Restorative Hydration Cream, can help reverse signs of aging by targeting the root cause of aging. You’ll get noticeable results in about two weeks and see optimal results in about 90 days.

For more information, please contact: 1800 6220

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